Abstract
ASO Visual Abstract: Adjuvant Radiotherapy After Pancreaticoduodenectomy for Margin-Negative, Node-Positive Pancreatic Ductal Adenocarcinoma: A Nationwide Analysis
Annals of surgical oncology, 42018251
22 Apr 2026
PMID: 42018251
Abstract
This nationwide National Cancer Database analysis evaluated whether adjuvant radiotherapy improves survival in patients with margin-negative, node-positive pancreatic ductal adenocarcinoma after pancreaticoduodenectomy. Using propensity-matched cohorts, adjuvant radiotherapy provided only a modest survival benefit overall and for stage IIB patients, with no benefit observed in stage III patients. Findings suggest that routine use of adjuvant radiotherapy in R0N+ pancreatic ductal adenocarcinoma should be individualized, balancing limited benefit against treatment burden (https://doi.org/10.1245/s10434-026-19566-5).
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Details
- Title
- ASO Visual Abstract: Adjuvant Radiotherapy After Pancreaticoduodenectomy for Margin-Negative, Node-Positive Pancreatic Ductal Adenocarcinoma: A Nationwide Analysis
- Creators
- Muhammad Muntazir Mehdi Khan - Allegheny Health NetworkEdward Anthony Joseph - Allegheny Health NetworkMuhammad Anees - Allegheny Health NetworkErin Grayhack - Allegheny Health NetworkYue Yin - Allegheny-Singer Research InstitutePaul Renz - Allegheny Health NetworkSricharan Chalikonda - Allegheny Health NetworkDavid L. Bartlett - Drexel University, SurgeryCasey J. Allen - Allegheny Health Network
- Publication Details
- Annals of surgical oncology, 42018251
- Publisher
- Springer Nature
- Number of pages
- 2
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:001746082100001
- Other Identifier
- 991022181972204721