Abstract
Abstract 14086: Do Outcomes Differ Between STEMI and NSTEMI Cardiogenic Shock?
Circulation (New York, N.Y.), v 146(Suppl_1)
08 Nov 2022
Abstract
Abstract only
Background:
Acute myocardial infarction relatedcardiogenic shock (AMI-CS) is a multifactorial syndrome with high morbidity andmortality. Contemporary, real-world data comparing outcomes among patients withST-elevation myocardial infarction related CS (STEMI-CS) versus non-STEMI(NSTEMI-CS) is lacking.
Methods:
Using data from 17 sites from the CardiogenicShock Working Group (CSWG) registry, we compared the clinical characteristics,hemodynamic, and metabolic profiles between STEMI-CS and NSTEMI-CS patients. Between 2016 to 2020, data from 1110 adultpatient hospital admissions with the diagnosis of AMI-CS were collected. Patientswith available data within 24 hours of admission were stratified according to baselineand maximum SCAI Stage. We performed comparison between STEMI vs NSTEMI groupusing one-way Anova analysis.
Results:
Among 1,110 patients with AMI-CS, 731(65.8%) had STEMI-CS and 379 (34.2%) had NSTEMI-CS. Most patients were male andwhite. Compared with NSTEMI-CS patients, STEMI-CS patients were younger (63.8±12.3 vs 69.2 ± 12.3, p<0.001). Overall unadjusted in-hospital mortality was41%. Mortality was similar among STEMI-CS and NSTEMI-CS patients (43% vs 39%,p=0.23). Patients with out-of-hospital (OHCA) or in-hospital cardiac arrest (IHCA)had higher in-hospital mortality (55% vs 39%, p =0.002; 62%% vs 33%, p<0.001, respectively) (Fig 1A).Shock severity defined by SCAI Stage within 24 hours of admission (baseline)and throughout hospitalization (maximum) directly correlated with in-hospitalmortality in both STEMI- and NSTEMI-CS (Fig 1B).
Conclusion:
We report one of the largest contemporary analysesspecifically comparing outcomes with STEMI-CS and NSTEMI-CS. Cardiac arrest is an important determinant ofmortality and SCAI Stages are directly associated with poor outcomes in bothcohorts.
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Details
- Title
- Abstract 14086: Do Outcomes Differ Between STEMI and NSTEMI Cardiogenic Shock?
- Creators
- Mohit Pahuja - Georgetown UniversityShashank S Sinha - Alaska Heart and Vascular InstituteRachna Kataria - Massachusetts General HospitalVanessa Blumer - Duke UniversityJaime Hernandez-Montfort - Temple, TXManreet Kanwar - Pittsburgh, PAArthur R Garan - Columbia UniversityYijing Zhang - Boston, MANeil Harwani - Greensboro CollegeBORUI LI - Boston, MAPaulina Baca - Tufts Medical CenterFatou Dieng - Boston, MAJeffrey Marbach - Oregon Medical Research CenterAdnan Khalif - Allegheny Health NetworkSaraschandra Vallabhajosyula - Wake Forest UniversitySandeep Nathan - University of Chicago Medical CenterDaniel Burkhoff - Remsenburg, NYNavin K Kapur - Tufts Medical Centeron behalf of CSWG investigators
- Publication Details
- Circulation (New York, N.Y.), v 146(Suppl_1)
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Cardiology
- Other Identifier
- 991021932097104721