Abstract
Abstract 15307: Gender-Based Trends in Cardiac Transplant Complications and Related Outcomes in Heart Failure Patients in the United States - A 10 Year Analysis From a National Inpatient Database
Circulation (New York, N.Y.), v 140(Suppl_1 Suppl 1), pp A15307-A15307
19 Nov 2019
Abstract
IntroductionImmediate post-transplant complications (PTC) remain a significant cause of morbidity and mortality in heart failure patients undergoing cardiac transplant (CT).HypothesisWe sought to examine gender-based temporal trends in inpatient PTC during index hospitalization and related outcomes amongst heart failure patients who underwent CT in the United States from 2007 through 2016.MethodsWe used the National Inpatient Sample to identify adult heart failure patients who underwent CT and those who developed PTC during their index hospitalization (including graft rejection, infection, failure, and vasculopathy) using appropriate ICD9/ICD10 codes. Demographics and PTC related outcomes [rates of PTC, associated inpatient mortality (IM), length of stay (LOS) and hospital charges (CHG)] were compared between gender groups, and temporal trends in these outcomes were analyzed. Stata 15.0 was used for all statistical analysis.ResultsAmong 45.9 million heart failure patients, 19368 underwent CT from January 2007 to December 2016. Although, females were younger (50 vs 54 years; p<0.001), and had the similar burden of chronic comorbidities (Elixhauser index- 5.6 vs 5.6; p=0.18), they had higher rates of PTC (33% vs 24%; p<0.001) compared to men. Female gender was also associated with a higher likelihood of PTC (OR, p1.53, <0.001) on multivariate analysis (adjusted for age, race, comorbidities, hospital characteristics and US geographical regions). Over the decade, there was no significant change in the rates of PTC and associated IM but associated LOS and CHG have increased significantly for both men and women (Image).ConclusionsOur study demonstrated that females are at a higher risk of PTC during index hospitalization but associated IM is no different compared to males. Moreover, the rates of PTC and associated IM have not changed in both men and women despite advancements in post-transplant care over the last 10 years.
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Details
- Title
- Abstract 15307: Gender-Based Trends in Cardiac Transplant Complications and Related Outcomes in Heart Failure Patients in the United States - A 10 Year Analysis From a National Inpatient Database
- Creators
- Abhishek Chaturvedi - Internal Medicine, Allegheny General Hosp, Pittsburgh, PACraig Alpert - Cardiovascular Institute, Allegheny General Hosp, Pittsburgh, PAMatthew Lander - Cardiovascular Institute, Allegheny General Hosp, Pittsburgh, PAManreet Kanwar - Allegheny General Hosp, Pittsburgh, PARaymond Benza - Allegheny Health NetworkAmresh Raina - Cardiovascular Institute, Allegheny General Hosp, Pittsburgh, PA
- Publication Details
- Circulation (New York, N.Y.), v 140(Suppl_1 Suppl 1), pp A15307-A15307
- Publisher
- by the American College of Cardiology Foundation and the American Heart Association, Inc
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Medicine (Graduate); Cardiology
- Other Identifier
- 991021932189104721