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Association Between Dupilumab Therapy and Vitiligo in Atopic Dermatitis: Findings from a Real-World U.S. Database
Abstract

Association Between Dupilumab Therapy and Vitiligo in Atopic Dermatitis: Findings from a Real-World U.S. Database

S. Minhaj Rahman, Dylan Wambold, Omar Alani, Fahad Ahmed, Albert Zhou and Adel Haque
Journal of the American Academy of Dermatology, v 95(1), pp AB60-AB60
Jul 2026

Abstract

Background: Dupilumab, an IL-4/IL-13 inhibitor, is a mainstay therapy for moderate-to-severe atopic dermatitis (AD). Case reports and a recent systematic review have suggested dupilumab may precipitate new-onset vitiligo, though large-scale data remains limited. This study assessed the risk of incident vitiligo among dupilumab-treated AD patients using a national United States database.

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