Abstract
ChemInform Abstract: Chemoselective Alkylations with N‐ and C‐Metalated Nitriles
ChemInform, v 47(7), pp no-no
Jan 2016
Abstract
The reaction of N‐lithiated cyclohexanecarbonitrile with bifunctional electrophiles or a 1:1 mixture of methyl cyanoformate and benzyl bromide proceeds chemoselectively to afford 1‐alkylated cyclohexanecarbonitriles (III), (VI), and (XI), whilst the reaction of C‐magnesiated nitriles gives rise to 1‐acylated products such as (IV), (VIII), and (XII).
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Details
- Title
- ChemInform Abstract: Chemoselective Alkylations with N‐ and C‐Metalated Nitriles
- Creators
- Xun Yang - Duquesne UniversityDinesh Nath - Duquesne UniversityFraser F. Fleming - Duquesne University
- Publication Details
- ChemInform, v 47(7), pp no-no
- Publisher
- WILEY‐VCH Verlag
- Number of pages
- 1
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Chemistry
- Other Identifier
- 991020898501004721