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Abstract
Life Course Pathways From Childhood SES to Age-Related Declines in Kidney Function Across Adulthood
Innovation in aging, v 4(Suppl 1), pp 832-832
16 Dec 2020
Abstract
Age is a strong predictor of declines in kidney function across adulthood. Using data from 2,045 adults (ages 25-84) in the Midlife in the United States (MIDUS) study, we examined the life course pathways through which low parental education, through adult SES and body mass index (BMI), was associated with faster age-related declines in kidney function. Kidney function declines by 0.8 mL/min/1.73 m2 per year across adulthood. Lower parental education, through adult SES and BMI, was associated with higher kidney function among younger adults (Est = -1.61, SE = 0.62, 95%CI = -2.62, -0.60), but lower kidney function among older adults (Est = 0.93, SE = 0.51, 95%CI = 0.11, 1.79). The impact of early socioeconomic adversity on kidney function is initiated by kidney hyperfiltration in early adulthood and followed by faster declines and development into disease state in later adulthood.
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Details
- Title
- Life Course Pathways From Childhood SES to Age-Related Declines in Kidney Function Across Adulthood
- Creators
- Agus Surachman - Drexel University, Epidemiology and BiostatisticsAlexis Santos - Pennsylvania State UniversityJonathan Daw - Pennsylvania State UniversityLacy Alexander - Pennsylvania State UniversityChristopher Coe - University of Wisconsin–MadisonDavid Almeida - Pennsylvania State University
- Publication Details
- Innovation in aging, v 4(Suppl 1), pp 832-832
- Publisher
- Oxford University Press
- Number of pages
- 1
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Dana and David Dornsife School of Public Health; Epidemiology and Biostatistics
- Other Identifier
- 991021893415004721