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Patient Experiences with Fluticasone Propionate Nasal Spray and Rosacea-like Symptoms: Highlighting a Potential Rosacea Link
Abstract

Patient Experiences with Fluticasone Propionate Nasal Spray and Rosacea-like Symptoms: Highlighting a Potential Rosacea Link

Taylor Merkle, Ryan Rezaee, Caitlyn Curley and Erum Ilyas
Journal of the American Academy of Dermatology, v 95(1), b327
Jul 2026
DOI: https://doi.org/10.1016/j.jaad.2026.04.1309

Abstract

Prolonged usage of topical steroids is linked to steroid-induced rosacea (SIR). However, any association of the popular, and now over the counter, potent glucocorticoid containing fluticasone propionate (FP) nasal spray, with rosacea has not been established. A survey was created utilizing the Qualtrics platform with IRB approval and distributed both online and in-person. A total of 128 respondents were included in the analysis with 77% of individuals reporting usage and 36% with daily usage of FP. More than half, 59%, reported areas of their face were often pink or red with 29% also reporting blood vessel marks or spider veins on the face and 57% with pimples that come and go. Of those reporting the above rosacea-like symptoms, 27% believed somewhat or significant worsening occurred after FP usage. With 42% of individuals reporting to struggle with these symptoms and only 8% having discussed FP in relation to rosacea with their doctor, a gap in knowledge for both patients and providers is highlighted. Further research is needed to investigate any causal relationship between FP and rosacea which can in turn inform clinical guidance for the counseling of patients.

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