Abstract
fNIRS Outcomes for a Pilot Clinical Trial Combining Frontal tDCS With Walking Rehabilitation in Older Adults
Innovation in aging, v 4(Suppl 1), pp 792-793
16 Dec 2020
Abstract
This pilot study assessed a novel intervention to enhance both walking and executive function in older adults. The primary hypothesis was that eighteen sessions of frontal lobe tDCS combined with walking rehabilitation would be feasible, safe, and show preliminary efficacy. Eighteen participants were randomized to one of three intervention groups: active tDCS and rehabilitation with complex walking tasks (Active/Complex); sham tDCS and rehabilitation with complex walking tasks (Sham/Complex); or sham tDCS and rehabilitation with typical walking (Sham/Typical). Outcome measures included multiple tests of walking function, executive function, and prefrontal activity during walking as measured by functional near infrared spectroscopy (fNIRS). Of the three groups, the Active/Complex group demonstrated the broadest improvements across outcome measures including for prefrontal activity. The functional range of prefrontal activity in this group was increased considerably, as conceptualized by the Compensation Related Utilization of Neural Circuits Hypothesis. Frontal tDCS is a promising adjuvant to walking rehabilitation.
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Details
- Title
- fNIRS Outcomes for a Pilot Clinical Trial Combining Frontal tDCS With Walking Rehabilitation in Older Adults
- Creators
- David Clark - University of FloridaSudeshna Chatterjee - University of FloridaJared Skinner - Appalachian State UniversityPaige Lysne - , Gainesville, Florida, , Boone, North Carolina, , Gainesville, Florida, , Gainesville, Florida, , Gainesville, FloridaSamuel Wu - University of FloridaRonald Cohen - University of FloridaDorian Rose - University of FloridaAdam Woods - University of Florida Health Science Center
- Publication Details
- Innovation in aging, v 4(Suppl 1), pp 792-793
- Publisher
- Oxford University Press
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Physical Therapy (and Rehabilitation Sciences)
- Other Identifier
- 991021860323004721