Abstract
fNIRS differentiates cognitive workload between concussed adolescents and healthy controls
Frontiers in human neuroscience, v 12
2018
Abstract
Concussion remains a clinical diagnosis based on subjective and non-specific symptoms with additional supporting assessments, such as neurocognitive testing and, more recently, physical examination findings. However, there are no sensitive or specific biomarkers for establishing the diagnosis of concussion. Recent FDA-approval of a blood biomarker that correlates with blood on head computed tomography (CT) in the setting of head injury is a step forward, but since most concussions are not associated with positive head CT scans with blood, there remains a critical gap in the objective diagnosis of concussion. Neuroimaging, particularly fMRI, has been considered as a potential diagnostic modality for concussion, but results have been conflicting, as specific findings associated with injury appear to depend on the severity of injury, timing post-injury and potentially the age of the individual. Functional near infrared spectroscopy (fNIRS) is a potential diagnostic modality due to its portability and ease of use in natural environments, which enable the assessment of cognitive workload as a function of cerebral oxygenation change while performing tasks in the clinical setting (Ayaz et al 2013). We hypothesize that fNIRS is able to distinguish concussed subjects from healthy controls utilizing a standardized assessment, the King-Devick test (Galetta et al 2011), a rapid number-naming reading task.
Metrics
2 Record Views
Details
- Title
- fNIRS differentiates cognitive workload between concussed adolescents and healthy controls
- Creators
- Hasan Ayaz - Drexel University, School of Biomedical Engineering, Science, and Health SystemsKristy Arbogast - University of VirginiaFairuz Mohammed - Children's Hospital of PhiladelphiaRonni Kessler - Children's Hospital of PhiladelphiaLei Wang - Drexel University, Information ScienceEileen Storey - Children's Hospital of PhiladelphiaOlivia Podolak - Children's Hospital of PhiladelphiaMatthew Grady - Children's Hospital of PhiladelphiaAndrew Mayer - Mind Research NetworkCatherine McDonald - University of PennsylvaniaChristina Master - Children's Hospital of Philadelphia
- Publication Details
- Frontiers in human neuroscience, v 12
- Conference
- The 2nd International Neuroergonomics Conference (Philadelphia, Pennsylvania, United States, 27 Jun 2018–29 Jun 2018)
- Resource Type
- Abstract
- Language
- English
- Academic Unit
- Information Science; School of Biomedical Engineering, Science, and Health Systems
- Other Identifier
- 991019186667304721