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A Model of the Baroreceptor Reflex Neural Network
Book chapter

A Model of the Baroreceptor Reflex Neural Network

J. S. Schwaber, I. A. Rybak and R. F. Rogers
ICANN ’94, pp 102-105
09 Jan 2012

Abstract

Cardiac Frequency Feedback Control Loop Nucleus Tractus Solitarii Pressure Threshold Total Peripheral Resistance
The baroreceptor vagal reflex is an important part of the cardiovascular control system. It may be defined as the biological neural control system responsible for the short-term blood pressure regulation. A simplified scheme of the baroreceptor vagal reflex circuit is the following. Baroreceptors located in the great arteries provide the sensory information to second-order neurons located in the nucleus tractus solitarii (NTS) in the lower brainstem [5]. Via a network of intemeurons, the second-order neurons affect motor neurons which in turn control heart rate and total peripheral resistance and thus blood pressure [3]. The firstorder neurons (baroreceptors) encode each pressUre pulse with a frequencyadapting train of spikes [1]. One of the mysteries of the identiiied baroreflex related second-order neurons in NTS is that in spite of receiving direct monosynaptic inputs from the first-order neurons, they do not show any pulse-rhythmic activity that contains the frequency Component corresponding to cardiac frequency.

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