Book chapter
A Post-genomic View of the Mitochondrion in Malaria Parasites
Malaria: Drugs, Disease and Post-genomic Biology, pp 233-250
2005
PMID: 16265893
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Mitochondria in Plasmodium parasites have many characteristics that distinguish them from mammalian mitochondria. Selective targeting of malaria parasite mitochondrial physiology has been exploited in successful antimalarial chemotherapy. At present, our understanding of the functions served by the parasite mitochondrion is somewhat limited, but the availability of the genomic sequences makes it possible to develop a framework of possible mitochondrial functions by providing information on genes encoding mitochondrially targeted proteins. This review aims to provide an overview of mitochondrial physiology in this post-genomic era. Although in many cases direct experimental proof for their mitochondrial functionsmay not be available at present, descriptions of these potential mitochondrial proteins can provide a basis for experimental approaches.
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Details
- Title
- A Post-genomic View of the Mitochondrion in Malaria Parasites
- Creators
- A. B Vaidya - Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, USAM.W Mather - Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, USA
- Publication Details
- Malaria: Drugs, Disease and Post-genomic Biology, pp 233-250
- Series
- Current Topics in Microbiology and Immunology
- Publisher
- Springer Berlin Heidelberg; Berlin, Heidelberg
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000233456400009
- Scopus ID
- 2-s2.0-24144482399
- Other Identifier
- 991014877981104721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Immunology
- Microbiology