Book chapter
Brain Tumours
Re-Irradiation: New Frontiers, pp 127-142
2017
Abstract
Historically, radiation oncologists have approached re-irradiating brain tumours with caution due to the potential risks of central nervous system late toxicity, especially radionecrosis, which may occur months or years following treatment. There is, however, a paucity of prospective data addressing this approach. Re-irradiation of brain tumours is attracting more interest as our understanding of the tolerance of the brain to radiation evolves. Furthermore, developments in radiation treatment approaches, technology and imaging enable highly accurate targeting of biologically relevant tumour volumes. Thanks to recent advancements in molecular-targeted therapy, further exploration of the role of re-irradiation – primary or in combination with novel agents – is needed.
Metrics
6 Record Views
Details
- Title
- Brain Tumours
- Creators
- Joshua D. Palmer - The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteColin Champ - University of Pittsburgh Medical CenterSusan C. Short - CRUK Lung Cancer Centre of ExcellenceShannon E. Fogh - University of California, San Francisco
- Contributors
- Carsten Nieder (Editor)Johannes Langendijk (Editor)
- Publication Details
- Re-Irradiation: New Frontiers, pp 127-142
- Series
- Medical Radiology
- Publisher
- Springer International Publishing; Cham
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Scopus ID
- 2-s2.0-85007453533
- Other Identifier
- 991021897392104721