Book chapter
Chapter 61 - Image Informatics
Measuring Immunity, pp 707-712
2004
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This chapter discusses image informatics. The technical components for image acquisition, image handling, analysis, and interpretation are described, and applications in immunology are given. Progress in the understanding of tissues, their structure, function, and dynamics, and role in immunity critically relies on the precision and quality of information available. Improvements to obtain more structural information are not only critical to carry out a sensitive and reproducible phenotyping suitable for diagnosis of inflammation, but are also increasingly valuable to elucidate the downstream effects of gene function and gene products. Quantitative tissue information helps to model and understand the structure–functional relationships of cellular assemblies in normal and disease tissues and transplants. An automated morphometry in conjunction with image informatics—computer assisted imaging, data storage, analysis, and correlation of tissue images—serves this emerging requirement. Despite the enormous progress in digital microscopy and automated applications in cytology and molecular screening techniques, visual inspection remains the prevailing method for analyzing histological tissue sections in medical research, pharmacology, and clinical diagnostics. A discussion on high throughput image acquisition and digital tissue repositories is presented. Machine vision analysis of inflammation, object segmentation, and high-content morphometrical analysis are also presented.
Metrics
17 Record Views
Details
- Title
- Chapter 61 - Image Informatics
- Creators
- Andres Kriete - Drexel University
- Publication Details
- Measuring Immunity, pp 707-712
- Publisher
- Elsevier
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000310783900063
- Scopus ID
- 2-s2.0-84882840807
- Other Identifier
- 991019168980004721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Immunology
- Medical Laboratory Technology