Book chapter
Clostridium botulinum (Botulism)
Principles and Practice of Pediatric Infectious Diseases, pp 999-1006
2018
Abstract
Botulism is a neuroparalytic disease caused by the action of a heat-labile neurotoxin produced almost exclusively by Clostridium botulinum. Botulism is categorized by modes of acquisition: (1) foodborne botulism, which results from the ingestion of preformed toxin elaborated in food that was naturally contaminated with spores and improperly preserved; (2) infant botulism, which results from intestinal colonization, outgrowth, replication, and toxin elaboration after the ingestion of spores; and (3) other, which includes wound botulism resulting from contamination of wounds with spores, outgrowth, and toxin elaboration; adult intestinal toxemia botulism resulting from intestinal colonization and in vivo toxin production, usually in the context of abdominal surgical procedures, gastrointestinal tract abnormalities, and recent antibiotic treatment; and accidental botulism resulting from high-dose injection of toxin for treatment of muscular movement disorders or injection of an unlicensed product for cosmetic purposes. [1st paragraph]
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Details
- Title
- Clostridium botulinum (Botulism)
- Creators
- Sarah S. Long
- Publication Details
- Principles and Practice of Pediatric Infectious Diseases, pp 999-1006
- Publisher
- Elsevier
- Edition
- 5th
- Number of pages
- 8
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Pediatrics
- Scopus ID
- 2-s2.0-85055536668
- Other Identifier
- 991019335238404721