Book chapter
Clostridium botulinum (Botulism)
Principles and Practice of Pediatric Infectious Diseases, pp 1017-1024
2023
Abstract
Botulism is a neuroparalytic disease of humans and other animals caused by the action of a heat-labile neurotoxin produced almost exclusively by Clostridium botulinum. Botulism is categorized by modes of acquisition: (1) infant botulism, which results from intestinal colonization, outgrowth, replication, and toxin elaboration after the ingestion of spores; (2) foodborne botulism, which results from the ingestion of preformed toxin elaborated in food that was naturally contaminated with spores and improperly preserved; and (3) other, which includes wound botulism resulting from contamination of wounds with spores, outgrowth, and toxin elaboration; adult intestinal toxemia botulism, resulting from intestinal colonization and in vivo toxin production, usually in the context of abdominal surgical procedures, gastrointestinal tract abnormalities, and recent antibiotic treatment; and accidental botulism resulting from high-dose injection of toxin for treatment of muscular movement disorders or injection of an unlicensed product for cosmetic purposes. [1st paragraph]
Metrics
33 Record Views
Details
- Title
- Clostridium botulinum (Botulism)
- Creators
- Stephen S. ArnonSarah S. Long
- Publication Details
- Principles and Practice of Pediatric Infectious Diseases, pp 1017-1024
- Publisher
- Elsevier
- Edition
- 6th
- Number of pages
- 8
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Pediatrics
- Scopus ID
- 2-s2.0-85205169871
- Other Identifier
- 991020417561904721