Book chapter
Donation After Cardiac Death Organ Procurement and Transplantation
Atlas of Organ Transplantation, pp 25-36
31 Dec 2014
Abstract
The donation after cardiac death (DCD) donor, formerly referred to as the non–heart-beating donor, is a type of expanded-criteria donor. Over the past decade, DCD has been the fastest-growing source of transplanted organs in the United States, bringing full circle the history of organ donation (Reich and Manzarbeitia 2005). DCD organ transplantation is utilized in the United States, Europe, and Asia to boost the number of deceased donors and decrease the dire shortage of transplantable organs. DCD is characterized by irreversible absence of circulation, in contrast to donation after brain death, defined by irreversible cessation of all brain functions. Organ ischemia is minimized in the brain-dead donor because circulatory arrest typically occurs concurrently with perfusion of preservation solution and rapid core cooling. DCDs are less than ideal because the organs suffer ischemia during the prolonged periods between circulatory dysfunction, circulatory arrest, and subsequent perfusion and cooling. Furthermore, the surgical procedure for DCD organ recovery, the main focus of this chapter, is demanding and rushed.
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Details
- Title
- Donation After Cardiac Death Organ Procurement and Transplantation
- Creators
- David J. Reich - Drexel University
- Contributors
- Abhinav Humar (Editor)Mark L. Sturdevant (Editor)
- Publication Details
- Atlas of Organ Transplantation, pp 25-36
- Publisher
- Springer London; London
- Number of pages
- 12
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Surgery
- Scopus ID
- 2-s2.0-105008597158
- Other Identifier
- 991021959048204721