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EFFECT OF ADENOSINE ON VASCULAR WALL TISSUE PO2
Book chapter

EFFECT OF ADENOSINE ON VASCULAR WALL TISSUE PO2

Donald G. Buerk
Biomedical Engineering I, pp 276-279
1982

Abstract

Measurements of PO2 levels on the outer surface and in vascular wall tissue were made from the thoracic aorta and femoral artery (N = 5 dogs) with recessed oxygen electrodes. Adenosine (. 25 mg/kg) caused a transient increase in the vascular wall P02 of the thoracic aorta by a maximum of + 23. 2 ± 6. 0 (SE) torr from the control level of 37. 3 ± 8. 3 (SE) torr (p < .025). No significant change was measured in the femoral artery. The PO2 responses indicate different vasodilatory capabilities for the vasa vasorum in the outer walls of the two vessels and may explain why some blood vessels are more susceptible to atherosclerosis.

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