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Electrochemical Measurement of Rapid Dopamine Release in Perfused Cat Carotid Body during Onset of Hypoxia
Book chapter   Peer reviewed

Electrochemical Measurement of Rapid Dopamine Release in Perfused Cat Carotid Body during Onset of Hypoxia

Donald G. Buerk and Sukhamay Lahiri
Arterial Chemoreceptors, pp 193-195
1994
PMID: 7872084

Abstract

Carotid Body Catecholamine Release Linear Calibration Curve Nafion Membrane Propyl Alcohol
Evidence that dopamine (DA) may play a role in carotid body (CB) chemotransduction has been reviewed by Eyzaguirre and Zapata (1984). Gonzalez et al. (1992) recently reviewed current theories for O2 and acid chemotransduction mechanisms. Using CBs incubated with radiolabelled tyrosine, it has been shown that hypoxia releases DA from a newly synthesized pool, and that its release is dependent on Ca2+ (Fidone et al., 1982; Gonzalez & Fidone, 1977; Rigual et al., 1991). Acidic conditions or elevated K+ also cause DA release in superfused cat and rabbit CBs.

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Web of Science research areas
Cardiac & Cardiovascular Systems
Endocrinology & Metabolism
Physiology
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