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Emergence of Stable Functional Cliques in Developing Neural Networks
Book chapter   Peer reviewed

Emergence of Stable Functional Cliques in Developing Neural Networks

Myles Akin and Yixin Guo
Complex Networks & Their Applications X, pp 629-640
01 Jan 2022

Abstract

Cliques Computational neuroscience Multiplex networks
Complex networks constructed from neural correlations exhibit nonrandom structures hypothesized to be related to neural information processing. These networks can be characterized by topological features such as hubs, communities and small world connectivity. A particular network structure of interest is a clique - a fully connected subgraph - which may indicate the existence of underlying neural ensembles. We introduce a multilayer network method to observe the persistence of functional cliques over population bursts as well as their development as the underlying neural network forms connections. Using data from developing cultures on MEAs, we show that cliques become more numerous and persistent over population bursts as neural cultures age. These results provide evidence for the formation of neural ensembles in cultured neural networks.

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Web of Science research areas
Computer Science, Interdisciplinary Applications
Mathematics, Applied
Social Sciences, Mathematical Methods
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