Book chapter
Fibromyalgia: Clinical Presentation, Pathophysiology and Diagnosis
Voice Disorders in Fibromyalgia, pp 37-48
01 Jan 2025
Abstract
Fibromyalgia (FM) is a complex neurological disorder characterized by central sensitization, dysfunction in pain processing, and aberration in the descending inhibitory pathways. Alteration in muscle metabolism and mitochondrial dysfunction also may contribute to the pathophysiology of this syndrome. The clinical presentation of FM is diverse. Patients usually present with persistent localized or diffuse pain in addition to various non-painful comorbidities. The diagnosis of FM is based on the patient’s history and physical examination. Serologic biomarkers are used to exclude other disease entities. More research is needed to understand the complexity of this syndrome and its systemic manifestations.
Metrics
1 Record Views
Details
- Title
- Fibromyalgia: Clinical Presentation, Pathophysiology and Diagnosis
- Creators
- Abdul latif Hamdan - American University of Beirut Medical CenterRobert Thayer Sataloff - Drexel UniversityMary J. Hawkshaw - Drexel University
- Publication Details
- Voice Disorders in Fibromyalgia, pp 37-48
- Publisher
- Springer Cham
- Number of pages
- 12
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- College of Medicine; Otolaryngology (and Head and Neck Surgery)
- Scopus ID
- 2-s2.0-105021986979
- Other Identifier
- 991022197408204721