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Functional near-infrared spectroscopy in addiction treatment: Preliminary evidence as a biomarker of treatment response
Book chapter   Open access

Functional near-infrared spectroscopy in addiction treatment: Preliminary evidence as a biomarker of treatment response

Scott C. Bunce, Jonathan Harris, Kurtulus Izzetoglu, Hasan Ayaz, Meltem Izzetoglu, Kambiz Pourrezaei and Banu Onaral
Foundations of Augmented Cognition - 7th International Conference, AC 2013, Held as Part of HCI International 2013, Proceedings, v 8027, pp 250-258
2013
DOI: https://doi.org/10.1007/978-3-642-39454-6_26
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https://doi.org/10.1007/978-3-642-39454-6_26View
Published, Version of Record (VoR) Open Maybe Open Access (Publisher Bronze)

Abstract

Addiction alcoholism biomarker fMRI fNIRs functional magnetic resonance imaging functional near infrared spectroscopy Neuroimaging
There is growing evidence that there are functional changes in the brains of individuals with substance use disorders. Numerous studies utilizing functional magnetic resonance imaging (fMRI) have shown that drug cues elicit increased regional blood flow in reward-related brain areas among addicted participants that is not found among normal controls. This finding has prompted leading investigators to suggest fMRI might be useful as a diagnostic or prognostic biomarker of addiction severity. However, fMRI is too costly for routine use in most treatment facilities. Functional near-infrared spectroscopy (fNIRs) offers an alternative neuroimaging modality that is safe, affordable, and patient-friendly. This manuscript reviews evidence that fNIRs can be used to differentiate prefrontal cortical responses of current alcohol dependent participants from alcohol dependent patients in treatment for 90-180 days. Differential responses to both alcohol and natural reward cues in both groups suggests fNIRs might serve as a clinic-friendly neuroimaging technology to inform clinical practice.

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