Book chapter
Human PapillomaVirus Tests and Cervical Cytology
Laboratory Screening and Diagnostic Evaluation, pp.441-448
Apr 2022
Abstract
Human papillomavirus (HPV) is a group of more than 200 small, double-stranded deoxyribonucleic acid (DNA) viruses that infect the squamous epithelium and are transmitted through skin-to-skin contact. This chapter provides an overview of the pathophysiology, laboratory tests, indications, screening, and diagnosis of HPV. The majority of HPV types invade the cutaneous layer of the epithelium causing skin warts, while approximately 40 HPV types infect the mucosal epithelium and possess oncogenic properties. Spread through intimate contact such as vaginal, anal, and oral sexual activity, HPV is the most common sexually transmitted infection (STI) in the United States. While the majority of HPV infections are asymptomatic and/or become undetectable within 2 years, persistent infection with the hrHPV types is the most important factor for serious and potentially fatal disease. Virtually all cervical cancer is caused by HPV.
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Details
- Title
- Human PapillomaVirus Tests and Cervical Cytology
- Creators
- Kymberlee Ann Montgomery - Drexel University, College of Nursing and Health Professions
- Publication Details
- Laboratory Screening and Diagnostic Evaluation, pp.441-448
- Publisher
- Springer Publishing Company, Incorporated; United States
- Number of pages
- 8
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- College of Nursing and Health Professions; Office of the Associate Dean of Nursing
- Identifiers
- 991022048019204721