Book chapter
Implications of nutraceutical modulation of glutathione with cystine and cysteine in general health and otology
Occupational Hearing Loss, pp 534-554
2025
Abstract
The application of nutraceuticals in otolaryngology has been studied most extensively in otitis media, presbycusis, and benign positional paroxysmal vertigo. However, nutraceutical use also has been investigated in autoimmune inner-ear disease, noise-induced hearing loss, and otologic surgery. Research in other areas has been more extensive and serves to inform otologic research. Modulation of oxidative stress via glutathione, cystine, and cysteine has played a pivotal role in understanding the pathogenesis of prostate cancer and the advancement of human immunodeficiency virus (HIV) to acquired immunodeficiency syndrome (AIDS). Oxidative stress is also thought to contribute to neurodegenerative diseases. A discussion of the use of nutraceuticals in immune system function, HIV/AIDS pathogenesis, and neurodegenerative disorders provides well-researched examples to support a discussion of the use of nutraceuticals in otology. Knowledge of nutraceutical use in otology serves to encourage physicians to consider using these adjunctive treatments when appropriate and to encourage further research.
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Details
- Title
- Implications of nutraceutical modulation of glutathione with cystine and cysteine in general health and otology
- Creators
- Katherine MullenThomas A. KwyerRobert Thayer Sataloff
- Publication Details
- Occupational Hearing Loss, pp 534-554
- Publisher
- CRC Press
- Edition
- 4
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- College of Medicine
- Other Identifier
- 991021903962904721