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Introduction
Book chapter

Introduction

Olimpia Meucci
Chemokine Receptors and NeuroAIDS, pp 1-2
01 Oct 2009

Abstract

Alternative Therapeutic Strategy Chemokine Receptor Cognitive Disorder Drug Abuser Opioid Receptor
During the last two decades chemokine receptors have consistently been in the spotlight albeit for different reasons. They have “evolved” from coordinators of inflammatory/immune responses to HIV co-receptors, mediators of organogenesis and development, cancer metastases inducers, and neuromodulators. However, it seems that our knowledge of the physiological and pathological roles of this large subfamily of G-protein-coupled receptors has not yet reached a plateau. Novel and essential biological functions of chemokine receptors are continuously been discovered and each of these new discoveries has led to alternative therapeutic strategies that show promise in the treatment of several pathologies, including AIDS and AIDS-related conditions.

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