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Introductory Review of Computational Cell Cycle Modeling
Book chapter   Open access

Introductory Review of Computational Cell Cycle Modeling

Andres Kriete, Eishi Noguchi and Christian Sell
Cell Cycle Control, pp 267-275
14 May 2014
PMID: 24906317
url
https://europepmc.org/articles/pmc4133988View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Computer simulation System function Biological systems Cell cycle modeling Cell Cycle Computer Modeling Systems Biology
Recent advances in the modeling of the cell cycle through computer simulation demonstrate the power of systems biology. By definition, systems biology has the goal to connect a parts list, prioritized through experimental observation or high-throughput screens, by the topology of interactions defining intracellular networks to predict system function. Computer modeling of biological systems is often compared to a process of reverse engineering. Indeed, designed or engineered technical systems share many systems-level properties with biological systems; thus studying biological systems within an engineering framework has proven successful. Here we review some aspects of this process as it pertains to cell cycle modeling.

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Web of Science research areas
Biochemical Research Methods
Biochemistry & Molecular Biology
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