Book chapter
Monitoring committee in clinical trials
Translational Cardiothoracic Surgery, pp 355-358
2026
Abstract
Clinical trials constitute a cornerstone in the development of medical interventions, providing essential insights into safety and efficacy. This chapter delves into the pivotal role of monitoring committees, multidisciplinary groups overseeing trials to ensure participant safety and scientific integrity. It explores the types of monitoring committees, including Data Monitoring Committees, Clinical Events Committees, Site Monitoring Teams, and Ethics Committees. Emphasizing necessity, it delineates situations demanding monitoring committees, such as high-risk interventions and large-scale trials. Conversely, situations where monitoring committees may be unnecessary, such as low-risk interventions or simple trial designs, are outlined. The chapter highlights the importance, operational aspects, challenges, and considerations associated with monitoring committees. Future trends, incorporating advanced technologies and patient-centric approaches, are explored. In conclusion, monitoring committees are integral to ethical, scientifically rigorous, and safe clinical research, adapting to emerging trends for enhanced oversight and innovation.
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Details
- Title
- Monitoring committee in clinical trials
- Creators
- Anjani Ravi - Drexel University, College of MedicineTemiloluwa Daramola - Michigan Medicine
- Publication Details
- Translational Cardiothoracic Surgery, pp 355-358
- Publisher
- Elsevier
- Number of pages
- 4
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- College of Medicine
- Scopus ID
- 2-s2.0-105033428425
- Other Identifier
- 991022176177204721