Book chapter
Naturally Occurring Neuron Death and Its Regulation by Developing Neural Pathways
International Review of Cytology, pp 163-186
1982
PMID: 6749741
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This chapter describes the naturally occurring neuron death and its regulation by developing neural pathways. The chapter describes degenerating neurons and shows how the morphological expression of cell death is closely related to a neuron's state of maturity. The timing of natural cell death is also considered to define where natural neuron death fits into other aspects of neural development and neuron differentiation. A large proportion of neurons that are destined to die naturally have a capacity to differentiate normally. Experimental studies show the dependence that a neuron has on the cell population with which it ultimately connects. Removal of targets for certain populations of neurons accentuates the normal attrition of neurons during development. The chapter also discusses the possible functions of cell death to provide a comprehensive explanation for this phenomenon.
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Details
- Title
- Naturally Occurring Neuron Death and Its Regulation by Developing Neural Pathways
- Creators
- Timothy J Cunningham - Department of Anatomy, The Medical College of Pennsylvania, Philadelphia, Pennsylvania
- Publication Details
- International Review of Cytology, pp 163-186
- Publisher
- Elsevier Science & Technology
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:A1982NJ55200005
- Scopus ID
- 2-s2.0-0020004194
- Other Identifier
- 991014877946204721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cell Biology