Book chapter
Neurogenesis in the Adult Brain
Encyclopedia of Cell Biology: Volume 1-6, Second Edition, v 6, pp 336-343
2016
Abstract
Neurogenesis is the generation and incorporation of new neurons into brain circuits. Although this process is largely confined to early development, robust neurogenesis continues well into adulthood in several brain regions of many vertebrate species, including humans. Identifying the cellular and molecular factors that guide adult neurogenesis has provided insights into how stem cell niches are generated and maintained elsewhere in the body in adults and during development. These studies have also revealed how an organism’s physiological state can regulate these niches as well as the subsequent fates of the newly generated cells. Finally, while it remains unclear why neurogenesis persists specifically in certain regions and not others, accumulating evidence is revealing the importance of these adult-born neurons to brain function.
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Details
- Title
- Neurogenesis in the Adult Brain
- Creators
- M. R. Akins - Drexel UniversityA. D.R. Garcia - Drexel University
- Publication Details
- Encyclopedia of Cell Biology: Volume 1-6, Second Edition, v 6, pp 336-343
- Publisher
- Elsevier
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Biology; Neurobiology and Anatomy
- Scopus ID
- 2-s2.0-85158933122
- Other Identifier
- 991022237867804721