Book chapter
Non-Hodgkin’s Lymphoma
Radiation Oncology, pp 399-413
2008
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Non-Hodgkin’s lymphoma (NHL) is generally considered a systemic disease process in 80%–85% of patients. The majority are of B-cell origin, with a wide variety of clinical phenotypes. A multi-disciplinary approach for management is appropriate for most cases. Chemotherapy is the mainstay of treatment in the majority of symptomatic presentations. External-beam radiation therapy is an important treatment modality for limited, localized indolent NHL, as well as in stage I and II aggressive diseases. Immunotherapy (rituximab) is often added to chemotherapy either concurrently or sequentially for CD20-positive disease. This chapter focuses on the management of indolent and aggressive non-Hodgkin’s lymphoma, particularly follicular lymphoma, marginal zone lymphoma, gastric MALT, and diff use large-cell lymphoma, and examines:
Recommendations for diagnoses and staging proceduresThe staging systems and prognostic factorsTreatment recommendations for indolent NHL and the sup- porting peer-reviewed scientific evidenceTreatment recommendations for gastric MALT and the sup- porting peer-reviewed scientific evidenceThe use of systemic chemotherapy and immunotherapy in combination with localized radiation therapy for definitive treatment of stage I and II aggressive NHLFollow-up care and surveillance of survivors
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Details
- Title
- Non-Hodgkin’s Lymphoma
- Creators
- Theodore E. Yaeger - Caldwell Memorial HospitalJiade J. Lu - National University of SingaporeLuther W. Brady - Drexel University
- Publication Details
- Radiation Oncology, pp 399-413
- Series
- Medical Radiology
- Publisher
- Springer Berlin Heidelberg; Berlin, Heidelberg
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000267130300028
- Other Identifier
- 991019169644704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging