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Oral Prescription Management
Book chapter   Peer reviewed

Oral Prescription Management

Aman Sandhu and Parmvir Singh
Advances in experimental medicine and biology, v 1447, pp 131-138
2024
DOI: https://doi.org/10.1007/978-3-031-54513-9_12
PMID: 38724790

Abstract

Administration, Oral Adrenal Cortex Hormones - adverse effects Adrenal Cortex Hormones - therapeutic use Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Dermatitis, Atopic - drug therapy Histamine Antagonists - adverse effects Histamine Antagonists - therapeutic use Humans Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Janus Kinase Inhibitors - adverse effects Janus Kinase Inhibitors - therapeutic use
The treatment of atopic dermatitis (AD) with oral treatments has been limited in the past due to the increased risk of adverse effects associated with oral agents. However, in recent years, a shift toward the minimization of adverse effects has been explored. Although existing treatment options like oral corticosteroids and Immunosuppressive therapies have been utilized for acute flare-ups of AD, their long-term use is limited by adverse effects and the need for lab monitoring. New systemic treatment options such as Janus kinase (JAK) inhibitors are emerging as a promising therapy, due to their quick onset and antipruritic features. However, the black box warning associated with this medication class requires careful selection of appropriate candidates and patient education despite early favorable safety profiles seen in AD trials. Discussion of other oral agents, like antibiotics and antihistamines, and their role in AD management are also clarified.

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