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Principles of Anti-Infective Therapy
Book chapter

Principles of Anti-Infective Therapy

John S. Bradley and Sarah S. Long
Principles and Practice of Pediatric Infectious Diseases, pp 1460-1467
2018

Abstract

The selection of optimal antibiotic therapy for presumed bacterial infection is based on the balance of benefits and risks of specific therapy for each child. Prescribing the right antibiotic or antibiotics early in the course of serious infection can save a life or avoid substantial morbidity. Inappropriate antibiotic therapy given to a child with a viral infection exposes the child needlessly to antibiotic toxicities, adds to the selective pressure driving antibiotic resistance in bacteria, creates unnecessary costs to the medical system, and can divert attention from evaluation and management of the child’s condition. [1st paragraph]

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