Book chapter
Recent Advances in PolyArylEtherKetones and Their In Vitro Evaluation for Hard Tissue Applications
Handbook of Spine Technology, pp 423-437
01 Jan 2021
Abstract
The advent of thermoplastic semicrystalline polymeric materials in the design of medical devices has allowed for the widespread use of polymeric interbody spacers for spinal arthrodesis to treat spinal degeneration. These polymers come from the PolyArylEtherKetone class of materials which are inert, readily machined, and serializable and have mechanical modules closely matching bone. Unfortunately, the inert nature of this class of materials may prevent osseointegration and can potentially generate a negative immune response. To overcome the inert character of PolyArylEtherKetones, researches have investigated several approaches to improving the biological properties of this important class of material. This review summarizes the history of PolyArylEtherKetones within the context of spinal arthrodesis and the recent approaches to improving the osseointegrative properties of this polymer.
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Details
- Title
- Recent Advances in PolyArylEtherKetones and Their In Vitro Evaluation for Hard Tissue Applications
- Creators
- Boyle C. ChengAlexander K. YuIsaac R. SwinkDonald M. WhitingSaadyah AverickBoyle C. Cheng
- Publication Details
- Handbook of Spine Technology, pp 423-437
- Publisher
- Springer International Publishing; Cham
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- SOM Dean - Research Administration; Surgery; Neurosurgery
- Scopus ID
- 2-s2.0-85150538292
- Other Identifier
- 991021463555204721