Book chapter
Small‐Intestinal Hormones and Neurotransmitters
Practical Gastroenterology and Hepatology Board Review Toolkit
02 Sep 2016
Abstract
The gastrointestinal tract is the largest endocrine organ, producing more than 100 bioactive peptides, which regulate motility, secretion, absorption, and growth of the gut. These peptides are secreted from specialized endocrine cells that are interspersed throughout the luminal digestive tract and the pancreas. Several peptide hormones are used in a variety of diagnostic and therapeutic applications. Regulation of gastrointestinal hormone secretion is tightly controlled, and involves a complex interaction between nutrient stimuli, the enteric nervous system, and the central nervous system. Alteration in either hormone secretion or action results in rare but classic syndromes, which can be clinically symptomatic or silent. In this chapter, we describe the key peptide hormones, their physiologic and pathophysiological role, and their clinical applications.
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Details
- Title
- Small‐Intestinal Hormones and Neurotransmitters
- Creators
- James Reynolds - Drexel University
- Contributors
- Michael B Wallace (Editor)Bashar A Aqel (Editor)Keith D Lindor (Editor)Nicholas J Talley (Editor)Kenneth R Devault (Editor)
- Publication Details
- Practical Gastroenterology and Hepatology Board Review Toolkit
- Publisher
- John Wiley & Sons, Ltd; Oxford, UK
- Resource Type
- Book chapter
- Language
- English
- Scopus ID
- 2-s2.0-105001464709
- Other Identifier
- 991019353625904721