Book chapter
Vascular and Metabolic Effects of Nitric Oxide Synthase Inhibition Evaluated by Tissue PO2 Measurements in Carotid Body
Oxygen Transport to Tissue XX, pp 455-460
1998
PMID: 9889924
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The suspected role of nitric oxide (NO) in modulating chemosensory activity, and the origin and actual locations of nitric oxide synthase (NOS) in the carotid body (CB) are not clear. Wang et al. (1993) were the first to show that NOS is present in the CB from immunochemistry and NADPH diaphorase staining of rat CBs. Prabhakar et al. (1993) also found NADPH positive nerve fibers around cat CB glomus cells. Wang et al. (1993) attributed the origin of NOS primarily to sensory neurons in the petrosal ganglion. On the other hand, Grimes et al. (1995) presented immunohistochemical evidence that NOS innervation in the cat CB appears to be autonomic, originating from dispersed ganglion cells, and may be parasympathetic in nature. Hohler et al. (1994) also found neuronal NOS primarily associated with autonomic neurons in Wistar rat CBs.
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Details
- Title
- Vascular and Metabolic Effects of Nitric Oxide Synthase Inhibition Evaluated by Tissue PO2 Measurements in Carotid Body
- Creators
- Sukhamay Lahiri - University of PennsylvaniaDonald G. Buerk - University of Pennsylvania
- Publication Details
- Oxygen Transport to Tissue XX, pp 455-460
- Series
- Advances in Experimental Medicine and Biology
- Publisher
- Springer; Boston, MA
- Resource Type
- Book chapter
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000077323800056
- Scopus ID
- 2-s2.0-0032444019
- Other Identifier
- 991019231740004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Biotechnology & Applied Microbiology
- Medicine, Research & Experimental
- Physiology