Review
Evidence-Based Recommendations on the Use of Immunotherapies and Monoclonal Antibodies in the Treatment of Male Reproductive Cancers
Current oncology (Toronto), v 32(2), 108
14 Feb 2025
PMID: 39996908
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The incidence of male reproductive cancers, including prostate, testicular, and penile cancers, has risen in recent years, raising important health concerns. Prostate cancer is the second leading cause of cancer-related mortality in men, while penile cancer, though rare, typically affects men over 60. Testicular cancer, with a lifetime risk of about 0.4% in men, is most common among adolescents and young adults, decreasing sharply after the age of 40. Traditional treatments include chemotherapy, radiation, surgery, and combinations thereof, but advancements in immunotherapy and monoclonal antibodies are showing promising results, particularly for genitourinary cancers. These therapies, targeting immune checkpoints and tumor-specific antigens, are gaining traction as effective alternatives for resistant cases. This review provides evidence-based recommendations on current and emerging immunotherapy and monoclonal antibody treatments for male reproductive cancers, highlighting future directions to optimize patient outcomes.
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Details
- Title
- Evidence-Based Recommendations on the Use of Immunotherapies and Monoclonal Antibodies in the Treatment of Male Reproductive Cancers
- Creators
- Farhan Khalid - Monmouth Medical CenterZubair Hassan Bodla - University of Central FloridaSai Rakshith Gaddameedi - Monmouth Medical CenterRaymart Macaset - Monmouth Medical CenterKaran Yagnik - Monmouth Medical CenterZahra NiazPeter N. Fish - Monmouth Medical CenterDoantrang Du - Monmouth Medical CenterShazia Shah - Monmouth Medical Center
- Publication Details
- Current oncology (Toronto), v 32(2), 108
- Publisher
- MDPI
- Number of pages
- 20
- Resource Type
- Review
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:001429650000001
- Scopus ID
- 2-s2.0-85218467466
- Other Identifier
- 991022030045804721
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- Collaboration types
- International collaboration
- Web of Science research areas
- Oncology