Logo image
Lung Cancer, Proptosis, and Decreased Vision
Review   Peer reviewed

Lung Cancer, Proptosis, and Decreased Vision

David B Auerbach, Jurij R Bilyk and Judith E Wolf
Survey of Ophthalmology, v 43(5), pp 405-412
1999
PMID: 10340559

Abstract

amphotericin B chemotherapy fungal infection immunosupression mucormycosis orbital apex syndrome
A 48-year-old man presented to the emergency department with a 3-day history of decreased vision in a painful proptotic right eye. The patient was being treated with chemotherapy and radiation for non–small cell lung carcinoma. Examination showed visual acuity of hand motions, decreased motility, and an afferent pupillary defect on the right, consistent with an orbital apex syndrome. Neuroimaging revealed ”dirty” orbital fat and no paranasal sinus disease. Orbital biopsy initially showed only fibrosis; however, on subsequent biopsies, nonseptate hyphae later identified as mucormycosis was recovered. The patient survived with exenteration and systemic amphotericin B.

Metrics

12 Record Views
8 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
Web of Science research areas
Ophthalmology
Logo image