Review
Measuring salivary cortisol in biobehavioral research: A systematic review and methodological considerations
Brain, behavior, & immunity. Health, v 43, pp 100936-100936
01 Feb 2025
PMID: 39867845
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The assessment of salivary cortisol in community settings has gained popularity in biobehavioral research due to its noninvasive sampling, ease of handling and storage, and suitability for repeated sampling in short intervals. Ensuring consistent methodological practices for salivary cortisol is essential. This systematic review critically examines salivary cortisol collection procedures, data cleaning, and analysis to better understand its role in biobehavioral research within community populations. Fifty-eight articles met the inclusion criteria. Results indicated significant variability in study designs and cortisol measurement procedures, particularly regarding the biobehavioral role of cortisol, sampling periods, covariate considerations, cortisol analysis parameters, and data analysis plans. The review highlights commonly used and promising study designs while identifying methodological issues in cortisol measurement and analysis that should be addressed to improve comparability in future research.
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Details
- Title
- Measuring salivary cortisol in biobehavioral research: A systematic review and methodological considerations
- Creators
- Fanghong Dong - Washington Univ, Sch Med, St Louis, MO 63110 USAJustine S. Sefcik - Drexel University, Doctoral NursingElizabeth Euiler - Drexel University, Physical Therapy (and Rehabilitation Sciences)Nancy A. Hodgson - University of Pennsylvania
- Publication Details
- Brain, behavior, & immunity. Health, v 43, pp 100936-100936
- Publisher
- Elsevier
- Number of pages
- 34
- Grant note
- K23 NR018673 / National Institute of Nursing Research of the National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Nursing Research (NINR) NR01522601 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Review
- Language
- English
- Academic Unit
- Doctoral Nursing; Physical Therapy (and Rehabilitation Sciences)
- Web of Science ID
- WOS:001401512400001
- Scopus ID
- 2-s2.0-85213824905
- Other Identifier
- 991022017435004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Neurosciences
- Psychiatry