Review
Regulation of E2F: a family of transcription factors involved in proliferation control
Gene, v 237(2)
1999
PMID: 10521653
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Members of the E2F family of transcription factors are key participants in orchestration of the cell cycle, cell growth arrest and apoptosis. Therefore, an understanding of the regulation of E2F activity is essential for an understanding of the control of cellular proliferation. E2F activity is regulated by the retinoblastoma family of tumor suppressors and by multiple other mechanisms. This review will describe our current knowledge of these mechanisms which together constitute a highly complex network by which the cell cycle and cellular proliferation can be controlled.
Metrics
Details
- Title
- Regulation of E2F: a family of transcription factors involved in proliferation control
- Creators
- Adrian R BlackJane Azizkhan-Clifford
- Publication Details
- Gene, v 237(2)
- Publisher
- Elsevier
- Resource Type
- Review
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology
- Web of Science ID
- WOS:000082766300001
- Other Identifier
- 991014877988904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Genetics & Heredity