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Spider and wasp neurotoxins: pharmacological and biochemical aspects
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Spider and wasp neurotoxins: pharmacological and biochemical aspects

Renê de O. Beleboni, Andrea B. Pizzo, Andréia C.K. Fontana, Ruither de O.G. Carolino, Joaquim Coutinho-Netto and Wagner F. dos Santos
European Journal of Pharmacology, v 493(1), pp 1-17
2004
PMID: 15189759

Abstract

Ion channel Neurotoxin Receptor Spider Transporter and Neurotransmitter release Wasp
Venoms from several arthropods are recognized as useful sources of bioactive substances, such as peptides, acylpolyamines, and alkaloids, which show a wide range of pharmacological effects on synaptic transmission. In this work, we summarize and compile several biochemical and pharmacological aspects related to spider and wasp neurotoxins. Their inhibitory and stimulatory actions on ion channels, receptors, and transporters involved in mammalian and insect neurotransmission are considered.

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Pharmacology & Pharmacy
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