Article Geriatrics/Gerontology Medicine Medicine & Public Health Neurosciences Nutrition Primary Care Medicine Quality of Life Research Aging
Older adults experience weight loss the first six weeks after coronary artery bypass grafting (CABG) surgery and the more weight lost the lower their self-reported physical health as well as hospital readmission. Weight loss is a risk factor for malnutrition. Ischemia-reperfusion injury associated with the use of the cardiopulmonary bypass pump (CPB) during traditional (on-pump) CABG surgery causes catabolism. Off-pump surgery is performed without the use of CPB, avoiding the adverse effects of CPB. This study explored the extent to which the weight loss is attributed to the catabolism associated with CPB by comparing changes in weight (as measured by body mass index {BMI}) for gender, age (< 65 vs > 65 years), and pump status (on-pump vs off-pump) in primary isolated CABG patients using a longitudinal descriptive design. The total sample of 44 (mean age 64.32 + 9.026) included 22 cases (off-pump) and 22 age-matched controls (on-pump) of which there were 24 older and 20 younger participants. Within participants, BMI changed over time from preoperative, post-operative day 5 and 4-6 weeks post-discharge, F=3.88, p=0.030, regardless of age. The effect of pump status was not statistically signficant, although trends indicate off- pump patients had the smallest change in BMI between postdischarge and preoperative, than the on-pump patients (-0.25 + 1.07 vs -0.8 +1.42, respectively). Although the off-pump patients lost less weight over time than on-pump patients, this is not statistically signficant. Further study is needed to determine the mechanisms underlying weight loss in older post-operative CABG patients.
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Title
A COMPARISON OF CHANGES IN BODY MASS INDEX OVER TIME IN ON-PUMP AND OFF-PUMP CABG PATIENTS
Creators
R. A. DiMaria-Ghalili - University of Pennsylvania
Publication Details
The Journal of nutrition, health & aging, v 12(7), pp 423-423
Conference
3rd IANA (International Academy on Nutrition and Aging) Meeting Nutrition, Exercise & Alzheimer and Clinical Trials on Sarcopenia, 3rd (Santa Ana Pueblo, New Mexico, United States, 01 Aug 2008–02 Aug 2008)
Publisher
Springer-Verlag
Number of pages
1
Resource Type
Conference paper
Language
English
Academic Unit
College of Nursing and Health Professions
Other Identifier
991019520418304721
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