Conference paper
The Association between Depression and Cardiovascular Disease in women: a Prospective 18-Year Follow-up Study
P-133
The Menopause Society
2024 Annual Meeting of The Menopause Society (Chicago, Illinois, United States, 10 Sep 2024 - 14 Sep 2024)
Sep 2024
Featured in Collection : Drexel's Newest Publications
Abstract
Objective: Cardiovascular disease (CVD) continues to be the leading cause of death for women in the United States. Depression may be associated with incident CVD in women. Therefore, the objective of this study is to analyze the relationship between depressive symptoms and incident coronary artery disease (CAD).
Design: Women were recruited at outpatient radiology visits in 2004. Initial survey questions collected demographics, depression history, CAD risk factors including hypertension, diabetes, hypercholesterolemia, and family history of CVD, in addition to CAD-related events. CAD events were a composite and included angina, myocardial infarction, and coronary revascularization. The 18-year follow-up survey was distributed via mail, e-mail, and telephone. A Chi-Square test was performed to describe the association between depression and incident CAD. A Mantel-Cox test was conducted to show the incidence of CAD in those with and without depression over time. Results: 1,995 participants filled the initial survey and after 18 years, 383 (19.2%) women completed the survey. Women with baseline depression were more likely to have CAD. ( 2 p=0.002). Over 18 years, women with depression were more likely to develop incident CAD compared to women without baseline depression (Mantel Cox p-value = 0.002, Figure 1).
Figure 1: MantelCox regression showing time to the development of CAD in those with and without depression at baseline.
Abbreviations: coronary artery disease (CAD)
Conclusion: Depressive symptoms and the incidence of CAD, as well as an association between depressive symptoms at baseline and the development of CAD over time. Further research should examine the role depression may have in cardiac risk assessment.
Metrics
1 Record Views
Details
- Title
- The Association between Depression and Cardiovascular Disease in women: a Prospective 18-Year Follow-up Study
- Creators
- Schyler Catherine Said - Drexel University, College of MedicineErica Helena Crawford - Drexel University, College of MedicineMarie Teresa Tan - Drexel University, College of MedicineMaggie M Feng - Drexel University, College of MedicineHannah Elizabeth Daley - Drexel University, College of MedicineJenna Elizabeth Ehlert - Drexel University, College of MedicineEmma J Christensen - Pennsylvania State UniversityMatthew Nudy - Pennsylvania State UniversityXuezhi Jiang - Reading HospitalPeter F Schnatz - Reading Hospital
- Publication Details
- P-133
- Conference
- 2024 Annual Meeting of The Menopause Society (Chicago, Illinois, United States, 10 Sep 2024 - 14 Sep 2024)
- Publisher
- The Menopause Society
- Resource Type
- Conference paper
- Language
- English
- Academic Unit
- College of Medicine; Obstetrics and Gynecology
- Identifiers
- 991021903710604721