Conference paper
The association between adverse pregnancy outcomes and cardiovascular disease in menopausal women: results from a cross-sectional analysis
P-132
The Menopause Society
2024 Annual Meeting of The Menopause Society (Chicago, Illinois, United States, 10 Sep 2024 - 14 Sep 2024)
Sep 2024
Featured in Collection : Drexel's Newest Publications
Abstract
Objective: Previous research has shown that a history of gestational hypertension (gHTN), preeclampsia, and gestational diabetes (GDM) are associated with an increased risk of cardiovascular disease (CVD). This study aims to assess the association between a self-reported history of preeclampsia or eclampsia (PreE/E), gHTN, and GDM with CVD outcomes in postmenopausal women. Design: Our survey was administered to 1,995 women presenting for mammogram screening. History of hypertension, diabetes, smoking, hypercholesterolemia, PreE/E, GDM, gHTN, family history of coronary artery disease, menopause status, and various CVD metrics were collected. In this analysis, CVD was a composite outcome and included a history of myocardial infarction, angina, abnormal angiogram, coronary revascularization, and stroke. A Chi-square test was conducted to analyze associations between history of PreE/E, GDM, gHTN, a combination of all three, and CVD outcomes.
Results: A total of 383 (19.2%) women returned the survey. Mean age (±standard deviation) of women was 81.6 (±9.1) years. Forty (10.3%) women reported a history of CVD. Eleven women (2.8%) reported a history of PreE/E. Eight (2.1%) had a history of gHTN while 14 (3.6%) had a history of gestational diabetes. A self-reported history of gHTN was associated with CVD (χ2 p<0.001). Women with PreE/E or all three adverse pregnancy outcomes had a numerically higher prevalence of CVD, however this did not meet statistical significance (p=0.395 and p=0.441, respectively). There was no association between gestational diabetes and CVD (p=0.679).
Conclusion: A self-reported history of gHTN was shown to be associated with CVD in a population of postmenopausal women. PreE/E, gestation diabetes and a combination of the three was not found to be associated with CVD in this analysis. This study is limited by recall bias and small sample size. Future research is needed to understand the role adverse pregnancy outcomes may have in CVD development and risk stratification.
Metrics
1 Record Views
Details
- Title
- The association between adverse pregnancy outcomes and cardiovascular disease in menopausal women: results from a cross-sectional analysis
- Creators
- Marie Teresa Tan - Drexel University, College of MedicineJenna Elizabeth Ehlert - Drexel University, College of MedicineSchyler Catherine Said - Drexel University, College of MedicineErica Helena Crawford - Drexel University, College of MedicineMaggie M Feng - Drexel University, College of MedicineHannah Elizabeth Daley - Drexel University, College of MedicineEmma J Christensen - Pennsylvania State UniversityMatthew Nudy - Pennsylvania State UniversityXuezhi Jiang - Reading HospitalPeter F Schnatz - Reading Hospital
- Publication Details
- P-132
- Conference
- 2024 Annual Meeting of The Menopause Society (Chicago, Illinois, United States, 10 Sep 2024 - 14 Sep 2024)
- Publisher
- The Menopause Society
- Resource Type
- Conference paper
- Language
- English
- Academic Unit
- College of Medicine; Obstetrics and Gynecology
- Identifiers
- 991021903710804721