Files and links (1)
Published, Version of Record (VoR)Open Access (License Unspecified), Open
Conference paper
"The simplest way to go:" A mixed methods analysis of why women who inject drugs selected long-acting injectable cabotegravir instead of daily oral PrEP.....95% of women initiated CAB Lai PrEP !!!
AIDS 2024 25th International AIDS Conference
Jul 2024
Abstract
BACKGROUND: Women who inject drugs (WWID) have disproportionately high rates of HIV, and thus would benefit from HIV pre-exposure prophylaxis (PrEP). WWID who struggle with daily adherence may prefer long-acting injectable cabotegravir (CAB-LA) however, few studies have assessed product preference, and none have described the process of product selection among WWID who were offered both modalities.
METHODS: Quantitative data are from 82 English-speaking, cisgender WWID >18 years, who received a PrEP prescription (oral PrEP or CAB-LA) from a provider integrated within a syringe services program (SSP) in Philadelphia (USA). Qualitative data are from a subset who completed a semi-structured interview (n=18 who chose CAB-LA, n=7 who chose oral PrEP). All participants are part of an ongoing RCT designed to reduce HIV acquisition risk. We used thematic analysis to explore the process of product selection.
RESULTS: Most WWID selected CAB-LA (75/82). Higher frequency of injection drug use and higher average number of sexual partners were each associated with selecting CAB-LA (93% daily vs 70% less than daily, p=0.056; 1 vs 0, p<0.01, respectively). No matter which product WWID selected, the decision-making process was similar. Product selection, as described in participant interviews, was informed by their perceived risk for HIV exposure, if/how adherence might be impacted by their individual context (e.g., addiction severity), the brief individual counseling session they received prior to making their selection, and prior experience with oral and/or injectable medications. For WWID selecting CAB-LA, reducing day-to-day action to receive long-term prevention benefits was important, as few believed they would adhere daily. Those selecting oral PrEP expressed more medical mistrust and dislike of needles and injectable medications. All women felt supported in their product selection by their PrEP providers.
CONCLUSIONS: Nearly all WWID in our study selected CAB-LA, suggesting a strong preference for this modality in this group. Women, including those selecting oral PrEP, had strong rationales for their choice. Offering women a wider array of products to choose from will likely increase uptake, as it has for other sexual health tools, like contraceptives.
Metrics
38 Record Views
Details
- Title
- "The simplest way to go:" A mixed methods analysis of why women who inject drugs selected long-acting injectable cabotegravir instead of daily oral PrEP.....95% of women initiated CAB Lai PrEP !!!
- Creators
- Allison K Groves - Drexel University, Urban Health CollaborativeAlexis Roth - Drexel University, Urban Health CollaborativeK. Rivet Amico - University of Michigan–Ann ArborErin Christine McDowell - Drexel University, Community Health and PreventionK M Ward - Drexel UniversityEvan M Forman - Drexel University, Psychological and Brain Sciences (Psychology)S Palmer - Drexel UniversityA Crayton - Drexel UniversityD S Krakower - Harvard Medical SchoolAdam Carrico - University of MiamiK MimsTyler S Bartholomew - University of Miami
- Publication Details
- AIDS 2024 25th International AIDS Conference
- Conference
- AIDS 2024 25th International AIDS Conference, 25th (Munich, Germany, 20 Jul 2024–26 Jul 2024)
- Resource Type
- Conference paper
- Academic Unit
- Psychological and Brain Sciences (Psychology); Dana and David Dornsife School of Public Health; WELL Center; Community Health and Prevention
- Web of Science ID
- WOS:001311241400177
- Other Identifier
- 991022008406804721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology
- Infectious Diseases