Conference proceeding
3D imaging of lung tissue by confocal microscopy and micro-CT
Proceedings of SPIE, v 4257(1), pp 469-476
09 Jul 2001
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Two complementary techniques for the imaging of tissue subunits are discussed. A computer guided light microscopic imaging technique is described first, which confocally resolves thick serial sections axially. The lateral area of interest is increased by scanning a mosaic of images in each plane. Subsequently, all images are fused digitally to form a highly resolved volume exhibiting the fine structure of complete respiratory units of lung. A different technique described is based on microtomography. This method allows to image volumes up to 3x3x3 cm at a resolution of up to 7 microns. Due to the lack of strong density differences, a contrast enhancement procedure is introduced which makes this technique applicable for the imaging of lung tissue. Imaging, visualization and analysis described here are parts of an ongoing project to model structure and to simulate function of tissue subunits and complete organs.
Metrics
Details
- Title
- 3D imaging of lung tissue by confocal microscopy and micro-CT
- Creators
- Andres Kriete - Justus-Liebig-Universität GießenAndreas Breithecker - Universitätsklinikum Gießen und MarburgWigbert D Rau - Universitätsklinikum Gießen und Marburg
- Publication Details
- Proceedings of SPIE, v 4257(1), pp 469-476
- Conference
- Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, 12th (San Jose, California, United States, 20 Jan 2001–26 Jan 2001)
- Publisher
- Society of Photo-Optical Instrumentation Engineers (SPIE)
- Number of pages
- 8
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000171276900057
- Scopus ID
- 2-s2.0-0034872696
- Other Identifier
- 991019186686304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Engineering, Biomedical
- Optics
- Physics, Applied