Conference proceeding
A Novel Three-dimensional Direct Controlled Cell Assembling System
ADVANCES IN MATERIALS AND MATERIALS PROCESSING, PTS 1-3, v 652-654, pp 2079-2085
01 Jan 2013
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Solid freeform fabrication (SFF) technology has been widely used to fabricate three-dimensional (3D) cell constructs. As multi-cell construct is a heterogeneous object (He-Object), it is a trend of biomanufacturing to use SFF technology to fabricate multi-cell constructs. In this paper, a novel multi-nozzle deposition system, called as 3D direct controlled cell assembling (CA) system, was developed to fabricate 3D multi-cell constructs. The developed system design was demand-oriented and applied functional modular design method. As the key part of this system, the multi-nozzle system was designed and described in details. Experimental study was conducted and results showed that the system could meet the requirements of the process and be used to fabricate complex 3D cell constructs. By comparison, the developed system could precisely deposite biomaterials with high viscocity and form constructs with big size in continuous deposition mode.
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Details
- Title
- A Novel Three-dimensional Direct Controlled Cell Assembling System
- Creators
- Yu Li - Tsinghua UniversityLei Zhang - Tsinghua UniversityChangyong Liu - Tsinghua Univ, Grad Sch Shenzhen, Biomfg Engn Res Lab, Shenzhen, Peoples R ChinaYu Zhao - Tsinghua UniversityWei Sun - Drexel University
- Contributors
- Z Y Jiang (Editor)X H Liu (Editor)S H Jiao (Editor)J T Han (Editor)
- Publication Details
- ADVANCES IN MATERIALS AND MATERIALS PROCESSING, PTS 1-3, v 652-654, pp 2079-2085
- Series
- Advanced Materials Research
- Publisher
- Trans Tech Publications Ltd
- Number of pages
- 2
- Grant note
- 51235006 / Key projects of the National Natural Science Foundation 2012AA020506 / National High Technology Research and Development Program of Ministry of Science and Technology
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000320475901070
- Scopus ID
- 2-s2.0-84874264765
- Other Identifier
- 991019167695004721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Engineering, Manufacturing
- Materials Science, Multidisciplinary