Conference proceeding
Alginate strings and their applications in spinal injury
Proceedings of the IEEE 28th Annual Northeast Bioengineering Conference (IEEE Cat. No.02CH37342), v 2002-, pp 223-224
2002
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Abstract
We have optimized a method for producing strings of alginate bioconjugated with a laminin pentapeptide that aids in cell adhesion. These strings are 400-500 /spl mu/m in thickness. In vitro studies have shown that rat (NB2a) and human (SHSY5Y) neuroblastoma cell lines adhere to and differentiate on these modified alginate strings. These strings are strong enough to be surgically transplanted onto the spinal cord, and may ultimately help in bridging the gap at the injury site.
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Details
- Title
- Alginate strings and their applications in spinal injury
- Creators
- S Kanakasabai - Drexel UniversityM.A Wheatley
- Publication Details
- Proceedings of the IEEE 28th Annual Northeast Bioengineering Conference (IEEE Cat. No.02CH37342), v 2002-, pp 223-224
- Publisher
- IEEE
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000175970000112
- Other Identifier
- 991019168564204721
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- Web of Science research areas
- Engineering, Biomedical