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An Efficient Approach to Detect a Protein Community from a Seed
Conference proceeding

An Efficient Approach to Detect a Protein Community from a Seed

D.D Wu and Xiaohua Hu
2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, v 2005, pp 1-7
2005

Abstract

Bioinformatics Biological system modeling Biological systems community Databases Engineering profession Genetics Genomics graph Graph theory Power system modeling Protein engineering protein-protein interactions
Community structure is a topological property common to many networks. We present in this paper an efficient and accurate approach to detecting a community in a protein-protein interaction network from a given seed protein. Our experimental results show strong structural and functional relationships among member proteins within each of the communities identified by our approach, as verified by MIPS complex catalogue database and annotations.

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24 citations in Scopus

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