Conference proceeding
Analysis of Collagen Fiber Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging
Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, v 1
26 Jun 2013
Abstract
Achilles tendon ruptures are traumatic injuries that frequently occur in active individuals and result in significant medical expense. Common techniques for assessing outcomes of surgical repair and rehabilitation rely heavily on patient-based measures of pain and function. While these measures can provide evidence for recovery of functional performance, they do not directly assess tendon healing which, if insufficient, can lead to re-rupture. The clinical evaluation of collagen organization following Achilles tendon injury may provide a more accurate measure of healing than traditional, functional performance tests. It has been shown that changes in collagen organization precede and correlate with changes in mechanical properties in tendons [1–3] and that load and injury effect collagen organization [4–6]. Ultimately, if collagen organization could be quantified in vivo, it would represent a powerful, diagnostic tool to measure the progression of tendon healing, as well as to monitor damage accumulation due to injury.
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Details
- Title
- Analysis of Collagen Fiber Organization in Mouse Achilles Tendon Using High-Frequency Ultrasound Imaging
- Creators
- Corinne N Riggin - University of Pennsylvania, Philadelphia PA.Joseph J Sarver - University of PennsylvaniaBenjamin R Freedman - University of Pennsylvania, Philadelphia PA.Stephen J Thomas - University of Pennsylvania, Philadelphia PA.Louis J Soslowsky - University of Pennsylvania, Philadelphia PA.
- Publication Details
- Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, v 1
- Conference
- ASME 2013 Summer Bioengineering Conference (Sunriver, Oregon, United States, 26 Jun 2013–29 Jun 2013)
- Publisher
- American Society of Mechanical Engineers
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Scopus ID
- 2-s2.0-84894671622
- Other Identifier
- 991019176644304721