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Bioprinted Nanoparticles for Tissue Engineering
Conference proceeding

Bioprinted Nanoparticles for Tissue Engineering

Kivilcim Buyukhatipoglu, Robert Chang, Wei Sun, Alisa Morss Clyne and IEEE
2009 IEEE INTERNATIONAL CONFERENCE ON COMPUTATIONAL INTELLIGENCE FOR MEASUREMENT SYSTEMS AND APPLICATIONS
01 Jan 2009

Abstract

Computer Science Computer Science, Artificial Intelligence Computer Science, Theory & Methods Engineering Engineering, Electrical & Electronic Science & Technology Technology
Tissue engineering may require recreation of the complex, three-dimensional native tissue architecture. While bioprinting allows cell and bioactive factor deposition in a precise pattern, it remains difficult to manipulate and track cells and bioactive factors after printing. We now show that superparamagnetic nanoparticles can be printed in an alginate hydrogel or inside cells themselves with low cell toxicity. Both nanoparticles and cells loaded with nanoparticles can be moved within the alginate hydrogel using a low field magnet, and nanoparticles can be imaged within the three-dimensional structure by micro-computed tomography. These data suggest that nanoparticles may advance biomanufacturing capabilities.

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Web of Science research areas
Computer Science, Artificial Intelligence
Computer Science, Theory & Methods
Engineering, Electrical & Electronic
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