Conference proceeding
Classification of polypeptide spectra from rat liver samples
Proceedings of the IEEE 28th Annual Northeast Bioengineering Conference (IEEE Cat. No.02CH37342), v 2002-
2002
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Abstract
We use clustering-based algorithms to classify polypeptide spectra of treated rat liver samples obtained through surface enhanced laser desorption/ionization mass spectrometry (SELDI-MS). Variance analysis is used to extract useful features from the high dimensional datasets. The features are then clustered using a hierarchical clustering algorithm based on scaled Euclidean distances. The clusters created are found to be correlated to the toxicity of the rat liver samples.
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Details
- Title
- Classification of polypeptide spectra from rat liver samples
- Creators
- Lit-Hsin Loo - Drexel UniversityJ Quinn - Drexel UniversityJ Armitage - [RISE ICT/Acreo, Kista, Sweden]H Cordingley - [FBK CREATE-NET, Trento, Italy]S Roberts - FBK CREATE-NET Research CenterP.J BugelskiL HrebienM Kam
- Publication Details
- Proceedings of the IEEE 28th Annual Northeast Bioengineering Conference (IEEE Cat. No.02CH37342), v 2002-
- Publisher
- IEEE
- Resource Type
- Conference proceeding
- Language
- English
- Academic Unit
- Electrical and Computer Engineering
- Web of Science ID
- WOS:000175970000070
- Other Identifier
- 991019182775504721
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- Web of Science research areas
- Engineering, Biomedical